“April 2017 : Intensification of the Company’s international development with the appointment of a new CEO : Mrs Nawal Ouzren”
“Sensorion aims to become a major player in the development of inner ear disease treatments of and thus fulfill unmet medical needs”
"Our mission is to develop innovative and targeted treatments for inner ear diseases with vertigo, tinnitus, hearing loss"
" Sensorion, has received “French Tech Pass” certification, and thus joins an exclusive circle of innovative French technology companies with substantial development potential"

Tinnitus

These are phantom noises (i.e. not heard by those around the patients) which consist of buzzing or whistling heard in one or both ears or in the head, in the absence of any external sound source.  Tinnitus is a very common disorder in France and is reported to affect 1 to 8% of the population (up to 12 million French people suffer from occasional tinnitus 1).  These disturbances can be the symptom of Ménière’s disease, a neuronoma or otosclerosis or follow any kind of hearing loss.

Many predisposing factors exist: exposure to noise, a past history of head injury, barotrauma, vascular disorders, severe anaemia and ototoxic drugs.
Tinnitus is a true public health problem.  Twenty six percent of patients with tinnitus report that it adversely affects their quality of life by interfering with everyday activities (reading, sleeping, concentrating on complex tasks and interacting socially).  Patients suffering from tinnitus have a higher risk of anxiety and depression2 .

The intensity and frequency of tinnitus vary greatly and require individualised management depending on the extent of the handicap which they cause.
The current treatments offered do not really meet all of the medical needs described by patients.
Three types of therapy can be distinguished: 

  • Cognitive behavioural therapy: this is a short therapy intended to replace negative ideas and unproductive behaviour by thoughts and reactions which are consistent with reality with the ultimate aim of facilitating habituation to the effect.  Whilst it does not treat tinnitus, it does prevent some of its consequences on quality of life (irritability, anxiety and depression).
  • Sound therapy using auditory stimuli  which cancel out the troublesome sound.  This therapy is used particularly in the United States at a cost of $2,500 to $3,500 per patient and a treatment period of one to two years in order to be effective.  It was very widely performed in the 1980s although is now less commonly used.
  • Medical therapy: this does not target the tinnitus itself but its consequences and involves some medications including  antidepressants and anxiolytics.

There is currently no curative treatment and the palliative therapies do not really meet patients’ needs.  Treatments targeting hair cells or peripheral neurones could help to reduce the frequency and severity of attacks. It would thus have a direct effect on the tinnitus and indirectly improve patients’ lives by reducing absence from work by facilitating their social interactions and improving their quality of life.


[1] Chiffres de a journée nationale de l’audition
[2] Londero A. et al. Contribution of cognitive and behavioral therapy for patients with tinnitus: implication in anxiety and depression. Ann Otolaryngol Chir Cervicofac. 2004 Dec;121(6):334-45.