“April 2017 : Intensification of the Company’s international development with the appointment of a new CEO : Mrs Nawal Ouzren”
“Sensorion aims to become a major player in the development of inner ear disease treatments of and thus fulfill unmet medical needs”
"Our mission is to develop innovative and targeted treatments for inner ear diseases with vertigo, tinnitus, hearing loss"
" Sensorion, has received “French Tech Pass” certification, and thus joins an exclusive circle of innovative French technology companies with substantial development potential"

Ménière’s disease

Ménière’s disease is another vestibular pathology. It is a chronic disease described for the first time in 1861 by Prosper Ménière. Ipateints suffer from a combination of rotatory vertigo crises from 20 minutes to 2-3 hours (up to 6 hours in some patients), hearing loss and tinnitus. It is characterized by recurrent and unpredictable crises that accumulate over time.

In Europe, 1 person out of 5000 is affected, more predominantly women between 20 and 60 years old1.

The etiology is still unknown which make prevention or treatment difficult to develop, but various factors are considered: genetic background, history of head injury, allergy, infection, vascular or immune dysfunctions, and migraine (in 34% of patients)…

In Ménière disease, the endolymph is present in excess which could increase inner ear pressure and contribute to symptoms.

The major symptoms of the disease (vertigo, tinnitus, reduced hearing acuity) may be accompanied by balance difficulties or even falling, a sensation of aural fullness, nausea sometimes leading to vomiting, sweating, pallor, diarrhoea, involuntary eye movements (the term “nystagmus” is used) and headaches.  Extreme tiredness may occur after an attack because of the unpleasantness of the various symptoms.

The disease progresses rapidly and is difficult to predict, and the frequency of attacks varies between patients.

The current treatment is based on :

  • Treatment of vertigo crises by isolation of the patient and administering anti-vertigo medication, sedatives and/or antiemetics.
  • A specific treatment for Ménière’s disease does not exist yet. Depending on patient pathological profile, conservative or destructive treatment of vestibular function (drug or surgically-based) can be used. Some experimental treatment (such as deep nerve stimulation) may also be considered. In conclusion, the unmet medical need persists and social isolation associated with significant disabilities severely impairs patient quality of life.

[1] http://www.entrepatients.net/fr/sante/fiches-sante/meniere-maladie-de. Dernière consultation le 25 février 2015